WG 2: Organoid Formation

Organoid Formation

Stas Shvartsman

Calin Belta

Laurie Boyer

Yuhong Fan

Linda Griffith

Roger Kamm

Michael Levin

Ron Weiss

Objective: Direct the co-differentiation of pluripotent stem cells to achieve controlled spatial patterning of multicellular constructs by harnessing biochemical, bioelectrical, and biophysical cues with a focus on subsequent steps towards organoid formation.

 

Hypothesis: Coincident differentiation of divergent cell phenotypes with appropriate spatial control is required to achieve functional organoids.